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High-throughput sequencing of immunoglobulin heavy chain for minimal residual disease detection in B-lymphoblastic leukemia.

Rodolfo Patussi CorreiaRenato D PugaNair H MutoMaria Lucia de M LeeDavi C TorresRocio HassanNydia S BacalNelson HamerschlakPaulo V Campregher
Published in: International journal of laboratory hematology (2021)
We have developed a novel approach on high-sensitive assay for MRD detection in B-ALL, which could add clinical value in the management of patients, especially in cases negative for MRD by FC.
Keyphrases
  • high throughput sequencing
  • loop mediated isothermal amplification
  • label free
  • real time pcr
  • acute myeloid leukemia
  • bone marrow
  • high throughput