Impact of adjuvant chemotherapy and radiotherapy on tumour-infiltrating lymphocytes and PD-L1 expression in metastatic breast cancer.
Shu YazakiRoberto SalgadoTatsunori ShimoiMasayuki YoshidaSho ShiinoTomoya KanedaYuki KojimaHitomi Sumiyoshi OkumaTadaaki NishikawaKazuki SudoEmi NoguchiTakeshi MurataShin TakayamaAkihiko SutoYuichiro OheKan YonemoriPublished in: British journal of cancer (2022)
TILs decreased in metastatic tumours, particularly in patients who relapsed after adjuvant chemotherapy. Changes in TILs from primary to metastatic sites could be a prognostic factor after recurrence.
Keyphrases
- prognostic factors
- metastatic breast cancer
- squamous cell carcinoma
- small cell lung cancer
- acute lymphoblastic leukemia
- early stage
- acute myeloid leukemia
- locally advanced
- multiple myeloma
- diffuse large b cell lymphoma
- radiation therapy
- hodgkin lymphoma
- peripheral blood
- radiation induced
- free survival
- rectal cancer