CD8+CD103+ tissue-resident memory T cells convey reduced protective immunity in cutaneous squamous cell carcinoma.
Chester LaiGeorge Stewart ColtartAndrew ShapanisConor HealyAhmad AlabdulkareemSara SelvendranJeffrey TheakerMatthew SommerladMatthew J J Rose-ZerilliAymen Al-ShamkhaniEugene HealyPublished in: Journal for immunotherapy of cancer (2021)
These results highlight CD8+CD103+ TRMs as an important functional T-cell subset associated with poorer clinical outcome in this cancer.