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Clinical Course of SARS-CoV-2 Infection in Adults with ESKD Receiving Outpatient Hemodialysis.

Ana Cecilia BardossyLauren KorhonenSabrina SchatzmanPaige GableCarolyn HerzigNicole E BrownElizabeth M BeshearseKate VarelaSarah SabourAmanda K LyonsRahsaan OvertonMatthew HudsonAlfonso C Hernandez-RomieuJorge AlvarezKaylin RomanMark WengElizabeth SodaPriti R PatelCrystal GrateLorien S DalrympleRebecca L WingardNatalie J ThornburgAlison S Laufer HalpinJennifer M FolsterMelissa Tobin-D'AngeloJanice LeaIbironke ApataL Clifford McDonaldAllison C BrownPreeta K KuttyShannon Novosad
Published in: Kidney360 (2021)
Patients with ESKD on maintenance dialysis remained persistently and intermittently SARS-CoV-2-RT-PCR positive. However, of the 15 participants, only one had infectious virus, on day 14 after symptom onset. Most participants mounted an antibody response, including neutralizing antibodies. Participants continued having RT-PCR-positive results in the presence of SARS-CoV-2-specific antibodies, but without replication-competent virus detected.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • chronic kidney disease
  • end stage renal disease
  • peritoneal dialysis
  • dengue virus
  • disease virus