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Pharmacokinetic Evaluation of New Drugs Using a Multi-Labelling Approach and PET Imaging: Application to a Drug Candidate with Potential Application in Neuromuscular Disorders.

Rossana PassannanteVanessa Gómez-VallejoMaialen Sagartzazu-AizpuruaLaura Vignau ArsuagaPablo Marco-MorenoGarazi AldanondoAinara Vallejo-IllarramendiPablo AguiarUnai CossíoAbraham MartínJonas BergareLee KingstonCharles S ElmoreMiguel Ángel Morcillo AlonsoPablo FerrónJesus M AizpuruaJordi Llop
Published in: Biomedicines (2023)
-O-Ar and tertiary amine groups as the main pathways. PET studies suggest that knowledge about metabolic pathways is paramount to interpret images.
Keyphrases
  • pet imaging
  • positron emission tomography
  • healthcare
  • deep learning
  • convolutional neural network
  • drug induced
  • case control
  • machine learning
  • risk assessment