Histologic, immunohistochemical, and scanning electron microscopic comparison of pre-iridal monocellular and fibrovascular membranes in normal and glaucomatous canine globes.

Leila BedosBruce H GrahnHelene PhilibertJohn CampbellLynne Sheila Sandmeyer

Published in: Veterinary ophthalmology (2021)

Pre-iridal monocellular membranes are a normal component of the anterior iris surface, and CD18 immunoreactivity suggests some cells within these are of leukocytic origin. SMA and CD117 labeling of monocellular membranes in glaucomatous, but not normal/control globes, suggest metaplastic cellular change secondary to intraocular pathology related to glaucoma.

Keyphrases

optic nerve
induced apoptosis
electron microscopy
high resolution
nk cells
cataract surgery
endoplasmic reticulum stress
cell death
drug induced