The two different profiles in heart failure with preserved ejection fraction and type 2 diabetes mellitus: ischemic and diabetic.
José Carlos Arévalo-LoridoJuana Carretero GómezAlicia Conde MartelOscar Aramburu BodasJoan Carles TrullásFrancisco Javier Carrasco SánchezLuis Manzano EspinosaJose Manuel Cerqueiro GonzálezCarmen Moreno GarcíaJesús Casado CerradaManuel Montero Pérez-BarqueroPublished in: Current medical research and opinion (2024)
Patients with T2DM and HFpEF, who had the poorest prognosis, were of two different profiles: either ischemic or DMC etiology. The first had a higher burden of cardiovascular disease and inflammation whereas the second had a higher prevalence of obesity and AF. The first had a slightly poorer prognosis than the second, though this finding was not significant.
Keyphrases
- cardiovascular disease
- type diabetes
- glycemic control
- risk factors
- ischemia reperfusion injury
- insulin resistance
- oxidative stress
- metabolic syndrome
- atrial fibrillation
- cerebral ischemia
- cardiovascular risk factors
- weight gain
- high fat diet induced
- adipose tissue
- body mass index
- skeletal muscle
- coronary artery disease
- blood brain barrier