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Multicentric Reticulohistiocytosis with Dermatomyositis-Like Features: A Case Report with Dermoscopy and Reflectance Confocal Microscopy Findings.

Banu FarabiMarielle JamgochianBabar K Rao
Published in: Journal of cutaneous pathology (2021)
Multicentric reticulohistiocytosis is an insidious-onset, non-Langerhans-cell histiocytosis affecting joints and skin. Early diagnosis is important to prevent destructive arthritis and disease-related complications. Reflectance confocal microscopy (RCM) is a technique that allows the visualization of the epidermis and superficial dermis non-invasively on a horizontal plane with quasi-histologic images of the skin. RCM features of non-Langerhans cell histiocytosis including Rosai-Dorfman disease, adult xanthogranuloma (AXG) and, juvenile xanthogranuloma (JXG) have been reported. However, RCM features of MRH have not previously been described. Herein, we present the RCM features of a case of MRH with dermoscopic and histopathologic features. This article is protected by copyright. All rights reserved.
Keyphrases
  • single cell
  • rheumatoid arthritis
  • deep learning
  • risk factors
  • machine learning
  • systemic lupus erythematosus
  • convolutional neural network