Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model.
Krystal HerlineFrances PrelliPankaj MehtaClaire MacMurrayFernando GoñiThomas M WisniewskiPublished in: Alzheimer's research & therapy (2018)
This study shows that acute treatment with an aβComAb can effectively improve performance in behavioral testing without reduction of amyloid plaque burden, and that peripherally administered IgG can affect levels of pathological species in the brain.