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Whole-genome methylome analysis reveals age-related diabetes risk factors.

Luo HaiZongzhi LiuWei ChenJie QiaoYingli Sun
Published in: Clinical and translational medicine (2020)
This study provides a new perspective on the relationship between age-related DNA methylation and insulin function. The hexokinase-1 (HK1)'s methylation level in the whole blood can be considered as a potential biomarker for the risk of diabetes in healthy individuals.
Keyphrases
  • type diabetes
  • dna methylation
  • glycemic control
  • risk factors
  • cardiovascular disease
  • genome wide
  • insulin resistance
  • skeletal muscle
  • adipose tissue