Evaluation of Host Gene Methylation as a Triage Test for HPV-Positive Women-A Cohort Study.

Pedro Vieira BaptistaMariana CostaJuliane HippeCarlos SousaMartina SchmitzAna-Rita SilvaAlfred HanselMario Preti

Published in: Journal of lower genital tract disease (2024)

The studied methylation panel has a high sensitivity and specificity for CIN3+ and reduces the rate of referrals for colposcopy, without relevant variation according to the rate of HPV16/18.

Keyphrases

genome wide
cervical cancer screening
high grade
dna methylation
emergency department
polycystic ovary syndrome
copy number
type diabetes
insulin resistance
structural basis
genome wide identification
adipose tissue
transcription factor
solid state
breast cancer risk
genome wide analysis