Prior Pulmonary Tuberculosis Is a Risk Factor for Asymptomatic Cryptococcal Antigenemia in a Cohort of Adults With Advanced Human Immunodeficiency Virus Disease.
Rachel M WakeNazir A IsmailShaheed V OmarFarzana IsmailCaroline T TiemessenThomas S HarrisonJoseph N JarvisNelesh P GovenderPublished in: Open forum infectious diseases (2022)
The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior tuberculosis was an independent risk factor for cryptococcal antigenemia (adjusted odds ratio, 2.72; 95% confidence interval, 1.13-6.52; P = .03) among patients with CD4 counts <100 cells/µL.
Keyphrases
- human immunodeficiency virus
- pulmonary tuberculosis
- hepatitis c virus
- antiretroviral therapy
- mycobacterium tuberculosis
- hiv aids
- hiv infected
- induced apoptosis
- hiv positive
- cell cycle arrest
- emergency department
- cell proliferation
- endoplasmic reticulum stress
- combination therapy
- smoking cessation
- replacement therapy
- drug induced
- men who have sex with men