Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria.
Daniel FresánSonia LuqueAdela Benítez-CanoLuisa SorlíMaría Milagro MonteroMarta De-AntonioVictoria VegaJason Alexander RobertsJuan P HorcajadaSantiago GrauPublished in: The Journal of antimicrobial chemotherapy (2023)
The administration of ceftaroline by prolonged infusion together with TDM may be a useful strategy for achieving the desired PK/PD target in these patients. However, more studies evaluating the relationship between PK/PD attainment and clinical outcomes are needed.