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Real-world experience of therapeutic drug monitoring and PK/PD achievement of ceftaroline administered by different infusion regimens in patients with confirmed infections caused by Gram-positive bacteria.

Daniel FresánSonia LuqueAdela Benítez-CanoLuisa SorlíMaría Milagro MonteroMarta De-AntonioVictoria VegaJason Alexander RobertsJuan P HorcajadaSantiago Grau
Published in: The Journal of antimicrobial chemotherapy (2023)
The administration of ceftaroline by prolonged infusion together with TDM may be a useful strategy for achieving the desired PK/PD target in these patients. However, more studies evaluating the relationship between PK/PD attainment and clinical outcomes are needed.
Keyphrases
  • end stage renal disease
  • low dose
  • ejection fraction
  • newly diagnosed
  • methicillin resistant staphylococcus aureus
  • prognostic factors
  • patient reported outcomes
  • multidrug resistant