In vitro investigation of head and neck cancer stem cell proportions and their changes following X-ray irradiation as a function of HPV status.
Paul Ambrose ReidPuthenparampil WilsonYanrui LiLoredana G MarcuAlexander H StaudacherMichael P BrownEva BezakPublished in: PloS one (2017)
CSC proportions in both cell lines were elevated after exposure and varied with time post irradiation. UM-SCC-47 displayed significant plasticity in repopulating the CSC phenotype in depleted cultures, which was not seen in UM-SCC-1.