Differential Chloride Secretory Capacity in Transepithelial Ion Transport Properties in Chronic Rhinosinusitis.
Justin P McCormickKyle HoffmanHarrison M ThompsonDaniel SkinnerShaoyan ZhangJessica GraysonBeate IllekDo-Yeon ChoBradford A WoodworthPublished in: American journal of rhinology & allergy (2020)
A substantial decrease in the Cl- secretory capacity of HSNE monolayers was demonstrated in CRS subjects. Data suggest that CFTR may contribute more to abnormal ion transport in CRS than CaCC.