Treatment Sequences After Discontinuing a Tumor Necrosis Factor Inhibitor in Patients With Rheumatoid Arthritis: A Comparison of Cycling Versus Swapping Strategies.
Aliza R Karpes MatusevichZhigang DuanHui ZhaoLincy S LalWenyaw ChanMaria E Suarez-AlmazorSharon H GiordanoJ Michael SwintMaria Angeles Lopez-OlivoPublished in: Arthritis care & research (2021)
Even though patients are more likely to cycle to a second TNFi than swap to a non-TNFi, those who swap to a non-TNFi are more likely to persist with the therapy. However, cycling to a TNFi is the less costly strategy.