Does mediastinal lymph node involvement influence the surgical outcome in malign pleural mesothelioma?
Mehmet Ali BedirhanYunus SeyrekOnur Volkan YaranCelal Bugra SezenLevent CanseverMuzaffer MetinPublished in: Acta chirurgica Belgica (2022)
In summary, our results suggested that mediastinal lymph node metastasis negatively influenced the prognosis of patients with T3 MPM, regardless of treatment by EPP or E/P. Under these circumstances, preoperative cervical mediastinoscopy or endobronchial ultrasound-guided transbronchial needle aspiration may be considered for patients with high-stage MPM who are scheduled for surgery with curative intent. In our study, N2 status was spotted as a significant factor affecting survival, nevertheless its significance in survival of pleural mesothelioma patients should be analyzed in multi-centered studies.
Keyphrases
- ultrasound guided
- lymph node metastasis
- lymph node
- fine needle aspiration
- end stage renal disease
- prognostic factors
- newly diagnosed
- ejection fraction
- squamous cell carcinoma
- minimally invasive
- peritoneal dialysis
- neoadjuvant chemotherapy
- papillary thyroid
- free survival
- early stage
- coronary artery disease
- patient reported