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Does mediastinal lymph node involvement influence the surgical outcome in malign pleural mesothelioma?

Mehmet Ali BedirhanYunus SeyrekOnur Volkan YaranCelal Bugra SezenLevent CanseverMuzaffer Metin
Published in: Acta chirurgica Belgica (2022)
In summary, our results suggested that mediastinal lymph node metastasis negatively influenced the prognosis of patients with T3 MPM, regardless of treatment by EPP or E/P. Under these circumstances, preoperative cervical mediastinoscopy or endobronchial ultrasound-guided transbronchial needle aspiration may be considered for patients with high-stage MPM who are scheduled for surgery with curative intent. In our study, N2 status was spotted as a significant factor affecting survival, nevertheless its significance in survival of pleural mesothelioma patients should be analyzed in multi-centered studies.
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