Increased risk of preneoplastic colonic lesions and colorectal carcinoma in acromegaly: multicenter case-control study.
Maria Florencia BattistoneKarina MiragayaAmelia RogozinskiMonica AgüeroAnalia AlfieriMaria Carolina BallarinoLaura BoeroKarina DanilowiczSabrina DiezMarina DonosoPatricia Fainstein-DayAlejandra FuriosoNatalia Ximena Garcia BasavilbasoMariela GlereanDebora Adela KatzMonica LotoMaria Susana Mallea-GilMarcela MartinezMaria Isabel SabateMarisa ServidioPatricia SlavinskyGraciela StalldeckerSoledad SosaGrabriela SzumanJulieta TkatchIgnacio CaldoDaniela LubienieckiMirtha GuitelmanPublished in: Pituitary (2020)
Our findings show an increased risk of preneoplastic colonic lesions and colorectal carcinoma in patients with chronic and sustained GH excess compared to a control group. This supports the recommendation to perform screening colonoscopy at diagnosis of acromegaly.