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A superlattice composite of Zn-Fe layered double hydroxide and graphene oxide for antitumor application.

Jiajun QiuMin XingLing ZhangHaifeng ZhangLu LiuDonghui WangWenhao QianXuanyong Liu
Published in: Journal of materials chemistry. B (2022)
A superlattice composite of Zn-Fe layered double hydroxide and graphene oxide was fabricated on the titanium surface and showed lamellar morphology. It was found for the first time that this superlattice composite could inhibit cell adhesion and proliferation, and cause cell death of the cholangiocarcinoma cell line RBE cells in vitro and show tumor inhibition effect in vivo .
Keyphrases
  • cell death
  • cell adhesion
  • cell cycle arrest
  • aqueous solution
  • induced apoptosis
  • heavy metals
  • signaling pathway
  • reduced graphene oxide
  • gold nanoparticles
  • risk assessment