Developmental vitamin D deficiency increases foetal exposure to testosterone.

Asad Amanat AliXiaoying CuiRenata Aparecida Nedel PertileXiang LiGregory MedleySuzanne Adele AlexanderAndrew J O WhitehouseJohn Joseph McGrathDarryl Walter Eyles

Published in: Molecular autism (2020)

This study is the first to show how an epidemiologically established environmental risk factor for ASD may selectively elevate testosterone in male embryonic brains. These findings provide further mechanistic support for the prenatal sex steroid theory of ASD.

Keyphrases

autism spectrum disorder
replacement therapy
attention deficit hyperactivity disorder
pregnant women
intellectual disability
human health
smoking cessation