Effects of alcohol and nicotine consumption on the development of apical periodontitis in rats: a correlative micro-computed tomographic, histological and immunohistochemical study.

K P PintoC M A FerreiraA F C GuimarãesCarolina Oliveira de LimaF R PiresL M SassoneEmmanuel João Nogueira Leal da Silva

Published in: International endodontic journal (2020)

Alcohol and nicotine consumption exacerbated the inflammatory response and the development of periradicular lesions in rats. The association of both substances enhanced their harmful effects.

Keyphrases

inflammatory response
alcohol consumption
lipopolysaccharide induced
immune response
electron microscopy