Plasma Neutrophil Gelatinase-Associated Lipocalin diagnosed acute kidney injury in patients with systemic inflammatory disease and sepsis.

Azrina Md RalibMohd Basri Mat NorJohn William Pickering

Published in: Nephrology (Carlton, Vic.) (2017)

Acute kidney injury is more common with sepsis than non-infectious SIRS. Plasma NGAL was diagnostic of AKI in both subgroups. The optimal cut-off for diagnosing AKI was higher in sepsis than in non-infectious SIRS. Addition of plasma NGAL improved the clinical model used to diagnose AKI.

Keyphrases

acute kidney injury
cardiac surgery
intensive care unit
oxidative stress
septic shock