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Plasma Neutrophil Gelatinase-Associated Lipocalin diagnosed acute kidney injury in patients with systemic inflammatory disease and sepsis.

Azrina Md RalibMohd Basri Mat NorJohn William Pickering
Published in: Nephrology (Carlton, Vic.) (2017)
Acute kidney injury is more common with sepsis than non-infectious SIRS. Plasma NGAL was diagnostic of AKI in both subgroups. The optimal cut-off for diagnosing AKI was higher in sepsis than in non-infectious SIRS. Addition of plasma NGAL improved the clinical model used to diagnose AKI.
Keyphrases
  • acute kidney injury
  • cardiac surgery
  • intensive care unit
  • oxidative stress
  • septic shock