Development of a novel cell line-derived xenograft model of primary herpesvirus 8-unrelated effusion large B-cell lymphoma and antitumor activity of birabresib in vitro and in vivo.

Tomohiro NishimoriTomonori HiguchiYumiko HashidaTakako UjiharaAyuko TaniguchiFumiya OgasawaraNaoya KitamuraIchiro MurakamiKensuke KojimaMasanori Daibata

Published in: Cancer medicine (2021)

These preclinical findings suggest the therapeutic potential of targeting c-MYC through BET inhibition in HHV8-unrelated effusion large B-cell lymphoma.

Keyphrases

diffuse large b cell lymphoma
cord blood
cancer therapy
cell therapy
drug delivery
mesenchymal stem cells
bone marrow