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Validation of Serostatus of Rheumatoid Arthritis Using ICD-10 Codes in Administrative Claims Data.

Hemin LeeJeffrey A SparksSu Been LeeKazuki YoshidaJoan E LandonSeoyoung C Kim
Published in: Pharmacoepidemiology and drug safety (2023)
ICD-10 codes (M05 and M06) can help identify RA serostatus in claims data, but their limitations should be acknowledged. The PPVs for seropositive and seronegative RA found in the Optum database were lower than those found in MarketScan, perhaps related to database variability or differing patient characteristics and clinical practice. When more restricted definitions of M05 and M06 were used, the PPVs for seropositive and seronegative RA improved to 79.2% and 89.5%, respectively. This article is protected by copyright. All rights reserved.
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