Alterations in whole-body arginine metabolism in chronic obstructive pulmonary disease.
Renate JonkerNicolaas E P DeutzMarcia L ErblandPaula J AndersonMarielle P K J EngelenPublished in: The American journal of clinical nutrition (2016)
In stable patients with moderate-to-severe COPD, endogenous arginine production is upregulated to support a higher arginine utilization that is unrelated to whole-body NO production. This trial was registered at clinicaltrials.gov as NCT01173354 and NCT01172314.