Genetic association tests in family samples for multi-category phenotypes.
Shuai WangJames B MeigsJosée DupuisPublished in: BMC genomics (2021)
Both proposed tests have correct type-I error rate and similar power. However, because the Wald statistics rely on computer-intensive estimation, it is less efficient than the score test in terms of applications to large-scale genetic association studies. We provide computer implementation for both multinomial and ordinal traits.