The presence of cerebral white matter lesions and lower skin microvascular perfusion predicts lower cognitive performance in type 1 diabetes patients with retinopathy but not in healthy controls-A longitudinal study.
Anna L EmanuelEelco van DuinkerkenMike P WattjesMartin KleinFrederik BarkhofFrank J SnoekMichaela DiamantEtto C EringaRichard G IJzermanErik H SernéPublished in: Microcirculation (New York, N.Y. : 1994) (2019)
These data fit the hypothesis that cerebral microangiopathy is a manifestation of generalized microvascular dysfunction, leading to lower cognitive performance.