Low serum albumin, aspartate aminotransferase, and body mass are risk factors for frailty in elderly people with diabetes-a cross-sectional study.

Ikumi YanagitaYuya FujiharaChikayo IwayaYuichi KitajimaMisuzu TajimaMasanao HondaYuji TeruyaHideko AsakawaTomoko ItoTerumi EdaNoriko YamaguchiYumi KayashimaMihoko YoshimotoMayumi HaradaShoji YoshimotoEiji AidaTashihiko YanaseHajime NawataKazuo Muta

Published in: BMC geriatrics (2020)

Hypoalbuminemia, low AST, and low BM are independent risk factors for frailty in elderly T2DM patients, strongly implying relative malnutrition in these frail patients. DHEA-S may be important for the maintenance of liver function and BM. A decrease in DHEA-S and an increase in the cortisol/DHEAS ratio may be involved in the mechanism of the effect of malnutrition in elderly T2DM patients.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
type diabetes
prognostic factors
peritoneal dialysis
cardiovascular disease
metabolic syndrome
adipose tissue
glycemic control
patient reported