Genomic, epidemiological and digital surveillance of Chikungunya virus in the Brazilian Amazon.
Felipe Gomes NavecaIngra ClaroMarta GiovanettiJaqueline Goes de JesusJoilson XavierFelipe Campos de Melo IaniValdinete Alves do NascimentoVictor Costa de SouzaPaola Paz SilveiraPaul S WikramaratnaMauricio SantillanaMoritz U G KraemerJosh QuickSarah C HillJulien ThézéRodrigo Dias de Oliveira CarvalhoVasco AzevedoFlavia Cristina da Silva SallesMárcio Roberto Teixeira NunesPoliana da Silva LemosDarlan da Silva CandidoGlauco de Carvalho PereiraMarluce Aparecida Assunção OliveiraCátia Alexandra Ribeiro MenesesRodrigo Melo MaitoClaudeth Rocha Santa Brígida CunhaDaniela Palha de Sousa CamposMarcia da Costa CastilhoThalita Caroline da Silva SiqueiraTiza Matos TerraCarlos F Campelo de AlbuquerqueLaura Nogueira da CruzAndré Luis de AbreuDivino Valerio MartinsDaniele Silva de Moraes Vanlume SimoesRenato Santana de AguiarSérgio Luiz Bessa LuzNicholas LomanOliver G PybusEster C SabinoOsnei OkumotoLuiz Carlos Junior AlcantaraNuno Rodrigues FariaPublished in: PLoS neglected tropical diseases (2019)
This study highlights the potential of combining traditional surveillance with portable genome sequencing technologies and digital epidemiology to inform public health surveillance in the Amazon region. Our data reveal a large CHIKV-ECSA outbreak in Boa Vista, limited potential for future CHIKV outbreaks, and indicate a replacement of the Asian genotype by the ECSA genotype in the Amazon region.