COL1A1 proximal promoter topology regulates its transcriptional response to transforming growth factor β.

Elena HitrayaSvetlana GaidarovaSonsoles Piera-VelazquezSergio A Jimenez

Published in: Connective tissue research (2024)

The topology of the COL1A1 proximal promoter is crucial in determining the transcriptional activity of the gene and its response to the stimulatory effects of TGF-β1.

Keyphrases

transforming growth factor
transcription factor
gene expression
epithelial mesenchymal transition
dna methylation
genome wide identification
genome wide
copy number
heat shock
signaling pathway
heat shock protein