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A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights.

Mohammad M Al-SaneaAhmad J ObaidullahMohamed E ShakerGarri ChilingaryanA F M Motiur RahmanNawaf A AlsaifHamad M Al KahtaniSultan A AlsubaieMohamed A Abdelgawad
Published in: Molecules (Basel, Switzerland) (2021)
These findings displayed a substantial basis of synthesizing further derivatives based on the 3-hydrazonoindolin-2-one scaffold for favorable targeting of breast cancer.
Keyphrases
  • tissue engineering
  • cell cycle
  • molecular docking
  • cancer therapy