Opioid Overdose Deaths with Buprenorphine Detected in Postmortem Toxicology: a Retrospective Analysis.

Rachel S WightmanJeanmarie PerroneRachel ScagosMaxwell KriegerLewis S NelsonBrandon D L Marshall

Published in: Journal of medical toxicology : official journal of the American College of Medical Toxicology (2020)

Decedents with buprenorphine detected on toxicology testing commonly had documented polysubstance use. Although data are limited, buprenorphine may provide some risk mitigation against full agonist opioid overdose including fentanyl. Further work should explore the use of postmortem concentrations of buprenorphine, norbuprenorphine, and other opioid metabolites to determine the role of buprenorphine in fatal overdose pharmacology.

Keyphrases

chronic pain
pain management
climate change
machine learning