Establishing a Dedicated Lung Cancer Biobank at the University Center Hospital of Nice (France). Why and How?
Kevin WashetineSimon HeekeChristelle BonnetaudMehdi Kara-BorniVéronique HofmanSandra LassalleCatherine ButoriElodie Long-MiraCharles Hugo MarquetteCharlotte CohenJérôme MourouxEric SelvaVirginie TangaCoraline BenceJean-Marc FélixLoic GazoppiTaycir SkhiriEmmanuelle GormallyPascal BoucherBruno ClémentGeorges DagherVéronique HofmanPaul HofmanPublished in: Cancers (2018)
Lung cancer is the major cause of death from cancer in the world and its incidence is increasing in women. Despite the progress made in developing immunotherapies and therapies targeting genomic alterations, improvement in the survival rate of advanced stages or metastatic patients remains low. Thus, urgent development of effective therapeutic molecules is needed. The discovery of novel therapeutic targets and their validation requires high quality biological material and associated clinical data. With this aim, we established a biobank dedicated to lung cancers. We describe here our strategy and the indicators used and, through an overall assessment, present the strengths, weaknesses, opportunities and associated risks of this biobank.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- squamous cell carcinoma
- healthcare
- small cell lung cancer
- small molecule
- polycystic ovary syndrome
- risk factors
- emergency department
- papillary thyroid
- high throughput
- copy number
- type diabetes
- drug delivery
- human health
- young adults
- risk assessment
- electronic health record
- skeletal muscle
- patient reported
- metabolic syndrome
- pregnancy outcomes
- clinical evaluation