The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer.

Lidia ChelliniMarco PieraccioliClaudio SetteMaria Paola Paronetto

Published in: Journal of experimental & clinical cancer research : CR (2022)

Collectively, our data uncover a new role of DHX9 in the control of the AR transcriptional program and establish the existence of an oncogenic DHX9/AR axis, which may represent a new druggable target to counteract PC progression.

Keyphrases

prostate cancer
transcription factor
quality improvement
gene expression
radical prostatectomy
circulating tumor
electronic health record
heat shock
nucleic acid
cell free
single molecule
big data
machine learning
heat shock protein