βArrestin1 regulates glucocorticoid receptor mitogenic signaling in castration-resistant prostate cancer.
Hamsa Thayele PurayilYehia DaakaPublished in: The Prostate (2022)
βArr1 binds GR that initiates mitogenic signaling cascades involved in the progression of PC to CRPC. The targeting of the βArr1-GR axis may provide a new opportunity to better manage the CRPC disease.
Keyphrases