Effects of anti-IL5 biological treatments on blood IgE levels in severe asthmatic patients: A real-life multicentre study (BIONIGE).
Marco ContoliPierachille SantusFrancesco MenzellaCindy RocchiDejan RadovanovicFederico BaraldiChiara MartelliSerena CasanovaCarlo BarbettaClaudio MichelettoNicola ScichiloneBianca BeghèElisiana CarpagnanoAlberto PapiPublished in: Clinical and translational allergy (2022)
Benralizumab but not mepolizumab, treatment led to a significant reduction of circulating IgE level. The study provides different and specific mechanisms of action for anti-IL5-pathway treatments.