Tumor-Infiltrating Lymphocytes and Macrophages in Intrahepatic Cholangiocellular Carcinoma. Impact on Prognosis after Complete Surgery.

Luca ViganoCristiana SoldaniBarbara FranceschiniMatteo CiminoAna LleoMatteo DonadonMassimo RoncalliAlessio AghemoLuca Di TommasoGuido Torzilli

Published in: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract (2019)

Tumor-infiltrating lymphocytes are associated with prognosis of ICC patients after complete surgery. CD3+ and CD8+ infiltrate is associated with higher survival and lower recurrence risk, while Foxp3+ infiltrate is associated with worse prognosis. CD3+ infiltrate allows refining prediction of prognosis in early tumors.

Keyphrases

minimally invasive
end stage renal disease
coronary artery bypass
ejection fraction
chronic kidney disease
newly diagnosed
nk cells
regulatory t cells
peritoneal dialysis
surgical site infection
acute coronary syndrome
atrial fibrillation
dendritic cells
patient reported
breast cancer risk