Fine mapping of genomic regions associated with female fertility in Nellore beef cattle based on sequence variants from segregating sires.

Gerson A Oliveira JuniorDaniel J A SantosAline S M CesarSolomon A BoisonRicardo V VenturaBruno C PerezJosé F GarciaJosé Bento S FerrazDorian J Garrick

Published in: Journal of animal science and biotechnology (2019)

The identification of heterozygous sires by positionally phasing SNP chip data and contrasting haplotype effects for previously detected QTL can be used for fine mapping to identify potential causal mutations and candidate genes. Genomic variants on genes MTERF2, RTBC, miRNA ENSBTAG00000037306, ENSBTAG00000040351, PRKDC, and RGS20, which are known to have influence on reproductive biological processes, were detected.

Keyphrases

copy number
genome wide
high density
air pollution
high resolution
dna methylation
bioinformatics analysis
early onset
electronic health record
big data
high throughput
gene expression
artificial intelligence
young adults
single cell
amino acid
genome wide identification