Interactions of Fibroblast Subtypes Influence Osteoclastogenesis and Alveolar Bone Destruction in Periodontitis.

Haicheng WangRenbin WangJingwen YangYuan FengShuyu Xu Qing-Guo Pei

Published in: Journal of inflammation research (2023)

Heterogeneous fibroblast subtypes affect the switch or development of periodontitis. A subtype (Cluster 4) played important role during alveolar bone destruction, by regulating other subtypes via EDA+FN paracrine.

Keyphrases

bone loss
bone mineral density
soft tissue
postmenopausal women
wound healing