Off-label intrathecal use of gadobutrol: safety study and comparison of administration protocols.

Merete HalvorsenCamilla Sæthre EdeklevJorunn Fraser-GreenGrethe LøvlandSvein Are Sirirud VatneholØivind GjertsenBård NedregaardRuth SlettebergGeir RingstadPer Kristian Eide

Published in: Neuroradiology (2020)

This prospective study showed that intrathecal administration of gadobutrol in a dose of 0.5 mmol is safe. Non-serious adverse events were to a lesser degree affected by the administration protocols, though preliminary data are given that side effects of intrathecal gadobutrol are dose-dependent.

Keyphrases

electronic health record
big data
machine learning
deep learning
clinical evaluation