Fixed doses of N8-GP prophylaxis maintain moderate-to-mild factor VIII levels in the majority of patients with severe hemophilia A.
Pratima ChowdaryManuel D CarcaoPål André HolmeVictor Jimenez YusteSteven R LentzJudi MøssLone H PoulsenChunduo ShenAlberto TosettoAllison WheelerElena SantagostinoPublished in: Research and practice in thrombosis and haemostasis (2019)
Prophylaxis with fixed intervals (Q4D/twice weekly) and fixed weight-based dosing (50/60 IU/kg) ensured >1 IU/dL FVIII trough levels in both adults and children.