Hydrochlorothiazide and increased risk of atypical fibroxanthoma and pleomorphic dermal sarcoma.
Thomas KuntzAlexander GrimmSilke C HofmannAlena-Lioba MichalowitzJörg SchallerMartin HellmichChalid AssafFrank OelligAlexander KreuterPublished in: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG (2024)
This study demonstrates a significantly higher use of HCTZ in patients with AFX/PDS compared to SCC/BCC. This result suggests that HCTZ may be a risk factor for AFX/PDS. Additionally, diabetes mellitus or its comorbidities may be associated with an increased risk for AFX/PDS.