Glucose-dependent inflammatory responses in obese compared to lean individuals.
Martin H LundqvistMaria João PereiraJan W ErikssonPublished in: Endocrine (2023)
Overall, hyperinsulinemia, hypo- and hyperglycemia led to suppression of several inflammatory markers and this tended to be more marked in individuals with obesity, insulin resistance and dysglycemia. Thus, acute glycemic or insulinemic variations do not seem to potentiate possible inflammatory pathways in the development of insulin resistance and disturbed glucose metabolism.
Keyphrases
- insulin resistance
- type diabetes
- adipose tissue
- metabolic syndrome
- high fat diet induced
- high fat diet
- skeletal muscle
- polycystic ovary syndrome
- liver failure
- glycemic control
- weight loss
- respiratory failure
- oxidative stress
- bariatric surgery
- drug induced
- bone mineral density
- weight gain
- body mass index
- diabetic rats
- mechanical ventilation
- physical activity