Comparing modeling strategies combining changes in multiple serum tumor biomarkers for early prediction of immunotherapy non-response in non-small cell lung cancer.
Frederik A van DelftMilou M F SchuurbiersMirte MullerSjaak A BurgersHuub H van RossumMaarten J IJzermanMichel M van den HeuvelHendrik KoffijbergPublished in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine (2023)
Non-response in NSCLC patients treated with ICIs can be predicted with a specificity >95% by combining multiple sequentially measured STMs in a prediction model. Clinical use is subject to further external validation.