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Chemosensitivity to doxorubicin of ER-positive/HER2-negative breast cancers with high 21-gene recurrence score: A study based on in vitro chemoresponse assay.

Sung-Gwe AhnSoong June BaeChangik YoonYoon Jin ChaHak Woo LeeSeung Ah LeeJoon Jeong
Published in: PloS one (2017)
The chemosensitivity measured by in vitro chemoresponse assay was different according to the RS. Our findings support that tumors with high RS has the chemosensitivity even though they are luminal/HER2-negative tumors.
Keyphrases
  • high throughput
  • drug delivery
  • genome wide
  • gene expression
  • estrogen receptor
  • dna methylation
  • free survival
  • young adults
  • single cell
  • genome wide analysis