A proliferation-inducing ligand-mediated anti-inflammatory response of astrocytes in multiple sclerosis.

Laurie BaertMahdia BenkhouchaNatalia PopaMashal C AhmedBenoit ManfroiJean BoutonnatNathalie SturmGilda RaguenezMarine TessierOlivier CasezRomain MarignierMitra AhmadiAlexis BroisatCatherine GhezziCyril RivatCorinne SonrierMichael HahneDominique BaetenRomain R VivesHugues Lortat-JacobPatrice N MarchePascal SchneiderHans P LassmannJose BoucrautPatrice H LaliveBertrand Huard

Published in: Annals of neurology (2019)

Our data show that APRIL mediates an anti-inflammatory response from astrocytes in MS lesions. This protective activity is not shared with BAFF. ANN NEUROL 2019;85:406-420.

Keyphrases

multiple sclerosis
inflammatory response
anti inflammatory
lipopolysaccharide induced
white matter
signaling pathway
electronic health record
lps induced
mass spectrometry
toll like receptor
big data
ms ms
neural network
immune response
deep learning