Impact of bisphenol A on cell viability and inflammatory cytokine production in human cervical epithelial cells.

Ourlad Alzeus Gaddi TantengcoManuel S VidalGiovana Fernanda Cosi Bento Ramkumar Menon

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)

Chemical exposure damage to the cervix can lead to adverse pregnancy outcomes. Our study showed that the BPA concentrations reported in pregnant subjects do not induce cervical cell toxicity . The decrease in apoptosis and increase in live cells may be a compensatory mechanism to preserve the integrity of the cervical epithelial layer.

Keyphrases

oxidative stress
pregnancy outcomes
cell cycle arrest
induced apoptosis
pregnant women
endothelial cells
endoplasmic reticulum stress
cell death
single cell
pi k akt
emergency department
preterm birth
stem cells
signaling pathway
mesenchymal stem cells
adverse drug
drug induced