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Classification of aplasia cutis congenita: a 25-year review of cases presenting to a tertiary paediatric dermatology department.

Dharshini SathishkumarM OgboliCelia Moss
Published in: Clinical and experimental dermatology (2020)
We conclude that the Frieden classification remains valid with some modifications. Type 3 ACC probably represents a mosaic RASopathy syndrome, while Type 7 could cover nongenetic ACC attributable to trauma. Type 8 should be subdivided into two subgroups: teratogenic and infective. Type 9 covers at least four subgroups. The classification will continue to evolve as new genes and pathomechanisms emerge.
Keyphrases
  • machine learning
  • deep learning
  • intensive care unit
  • genome wide
  • gene expression
  • dna methylation