Chrysophanol Regulates Cell Death, Metastasis, and Reactive Oxygen Species Production in Oral Cancer Cell Lines.
Po-Chih HsuChing-Feng ChengPo-Chun HsiehYi-Hsuan ChenChan-Yen KuoHuey-Kang SytwuPublished in: Evidence-based complementary and alternative medicine : eCAM (2020)
Chrysophanol has an anticancer effect on FaDu and SAS cell lines. There is an increase in subG1 accumulation, ROS production, and cell cycle G1 arrest after treatment with chrysophanol. On the other hand, chrysophanol inhibited cell migration/metastasis and EMT. We proposed that chrysophanol may be a good candidate compound on oral cancer treatment in the further.