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Atraumatic splenic rupture following IVIg for parvovirus B19 pure red cell aplasia post renal transplant.

Mark Kung Dah TiongJoshua CasanCatriona McLean
Published in: Transplant infectious disease : an official journal of the Transplantation Society (2019)
Parvovirus B19 (PB19) associated pure red cell aplasia (PRCA) is an uncommon but well described complication of immunosuppression post solid organ transplantation. We report a unique case of a renal transplant patient with PB19 associated PRCA who developed a spontaneous splenic rupture after receiving IVIg for persistent anemia. He subsequently required splenectomy. Within the spleen we subsequently identified PB19 affected cells.
Keyphrases
  • heavy metals
  • cell therapy
  • single cell
  • induced apoptosis
  • chronic kidney disease
  • risk assessment
  • mesenchymal stem cells
  • signaling pathway
  • oxidative stress
  • cell death